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Anti wrinkle blog

The Newest Anti-Wrinkle Brand You Probably Haven’t Heard Of

March 5, 2020

There is a relatively newer brand of anti-wrinkle injectable product available in Australia that reduces the likelihood of anti-wrinkle resistance, but the excitement around it seems to be kept behind select doctors’ doors.

When it comes to anti-wrinkle injections, there are currently three brands available in Australia. We’re all familiar with the most popular brand; it comes from America and it’s become a generic term for the treatment itself. Many of us also know about its less expensive yet less potent counterpart. Why aren’t there more people talking about the newer, third brand?

Part of it has to do with Therapeutic Goods Administration (TGA) regulations in Australia. Clinics that offer anti-wrinkle injections are not allowed to publish brand names on websites, on social media or in any other forms of advertising. This is because anti-wrinkle injections are classified as a prescription drug.

We can tell you the brand names in a free consultation, discuss the benefits of each brand and make recommendations, but regulations prevent us from posting the brand names online. Media outlets, news sites and blogs can use the names, just not anyone who offers injectables commercially. If you do see a clinic publishing brand names of anti-wrinkle injections or fillers, they’re technically breaking a regulation.

For general informational purposes of this article, we’ll call the most popular brand “B,” it’s less expensive/less potent counterpart “D” and the newest one will be brand “X.”

To be available in Australia, each brand must be approved by the TGA, which means that it must go through the same rigorous review processes as any pharmaceutical drug.

Brands B and D have been available in Australia since 1999 and 2000, which gave them a lot of time to build up a reputation. Brand X has only been available since 2014. With strict advertising regulations and a market that was dominated exclusively by two brands for 15 years, it would be difficult for any brand to grow. Brand X, however, has one special feature.

Anti-wrinkle injectable products are made from a live substance that can have cosmetic and therapeutic benefits when injected into the appropriate muscles. During the production process, this substance naturally develops proteins which assist in transport of the active substance to the muscle, but these proteins can also trigger your body to develop antibodies. This means there is a risk of developing resistance, and eventually immunity, to anti-wrinkle injections.

Brand X has added an extra purification step to the production process to remove the proteins. This means that you get the full effect of the active substance, but none of the extraneous proteins, so the risk of developing resistance is decreased.

Aesthetic Medical Practitioner reports that recent data has found evidence of antibodies developing in 13% of patients who use anti-wrinkle injections for medical purposes (which often require higher doses). The same article reports a more recent study that found evidence of antibodies developing in 7% of participants treated with product B, 6% of those with product D, and 30% of those who switched between brands. 0% of participants treated with product X showed evidence of developing antibodies.

Though the risk of developing resistance to anti-wrinkle injections is lower with brand X, the effect is still similar. A 2016 analysis of data collected from over 3,000 patients across 18 trials found that brands X and B were equally effective1

Our Cosmetic Nurse Ivona who works in both cosmetic and neurovascular medicine says that a few hospitals have begun to use brand X preferentially to decrease the risk of resistance, especially where larger doses are required.

Our Clinical Director, Dr Garry Cussell, often favours product X, but it can also depend on the client. We offer all three brands, and we’re happy to discuss them with you directly and make recommendations so that you can make an informed decision about which one is right for you.

  1. Bonaparte JP, Ellis D, Quinn JG, Rabski J, Hutton B. A Comparative Assessment of Three Formulations of B Toxin Type A for Facial Rhytides: A Systematic Review with Meta-Analyses. Plastic and Reconstructive Surgery. 2016;137:1125-40.

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